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Induction of anti-tumor immunity by human telomerase reverse transcriptase (hTERT) and viral-derived peptides in breast cancer mouse models

Induction of anti-tumor immunity by human telomerase reverse transcriptase (hTERT) and viral-derived peptides in breast cancer mouse models

Human telomerase reverse transcriptase (hTERT) is the most common tumor-associated antigen (TAA) and its activity is upregulated in more than 90% of cancers. Therefore, its targeting can be used in cancer immunotherapy. In continuing with our previous study, we evaluated hTERT derived peptides conju...

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Bibliographic Details
Main Authors: Fanuel Songwe, Gholam Ali Kardar, Abasalt Hosseinzadeh Colagar, Mehdi Ghorbani, Amir Mohammadi
Other Authors: Department of Biological Sciences, Faculty of Science and Technology Midlands State University Gweru, Zimbabwe
Format: research article
Language:English
Published: Research Square 2023
Subjects:
hTERT
MHC
Peptide-based vaccine
Viral peptide
Cancer immunotherapy
Online Access:https://cris.library.msu.ac.zw//handle/11408/5646
https://doi.org/10.21203/rs.3.rs-2751351/v1
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https://cris.library.msu.ac.zw//handle/11408/5646
https://doi.org/10.21203/rs.3.rs-2751351/v1