Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study

Objectives To identify and measure the place-specific determinants that are associated with adverse maternal and perinatal outcomes in the southern region of Mozambique. Design Retrospective cohort study. Choice of variables informed by literature and Delphi consensus. Setting Study conducted duri...

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Main Authors: Makanga, Prestige Tatenda, Sacoor, Charfudin, Schuurman, Nadine, Lee, Tang, Vilanculo, Faustino Carlos, Munguambe, Khatia, Boene, Helena, Ukah, Ugochinyere Vivian, Vidler, Marianne, Magee, Laura A, Sevene, Esperanca, von Dadelszen, Peter, Firoz, Tabassum, CLIP Working Group
Format: Article
Language:English
Published: BMJ Publishing Group 2021
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Online Access:https://bmjopen.bmj.com/content/bmjopen/9/2/e024042.full.pdf
http://hdl.handle.net/11408/4398
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author Makanga, Prestige Tatenda
Sacoor, Charfudin
Schuurman, Nadine
Lee, Tang
Vilanculo, Faustino Carlos
Munguambe, Khatia
Boene, Helena
Ukah, Ugochinyere Vivian
Vidler, Marianne
Magee, Laura A
Sevene, Esperanca
von Dadelszen, Peter
Firoz, Tabassum
CLIP Working Group
author_facet Makanga, Prestige Tatenda
Sacoor, Charfudin
Schuurman, Nadine
Lee, Tang
Vilanculo, Faustino Carlos
Munguambe, Khatia
Boene, Helena
Ukah, Ugochinyere Vivian
Vidler, Marianne
Magee, Laura A
Sevene, Esperanca
von Dadelszen, Peter
Firoz, Tabassum
CLIP Working Group
author_sort Makanga, Prestige Tatenda
collection DSpace
description Objectives To identify and measure the place-specific determinants that are associated with adverse maternal and perinatal outcomes in the southern region of Mozambique. Design Retrospective cohort study. Choice of variables informed by literature and Delphi consensus. Setting Study conducted during the baseline phase of a community level intervention for pre-eclampsia that was led by community health workers. Participants A household census identified 50493 households that were home to 80483 women of reproductive age (age 12–49 years). Of these women, 14617 had been pregnant in the 12 months prior to the census, of which 9172 (61.6%) had completed their pregnancies. Primary and secondary outcome measures A combined fetal, maternal and neonatal outcome was calculated for all women with completed pregnancies. Results A total of six variables were statistically significant (p≤0.05) in explaining the combined outcome. These included: geographic isolation, flood proneness,access to an improved latrine, average age of reproductive age woman, family support and fertility rates. The performance of the ordinary least squares model was an adjusted R2 =0.69. Three of the variables (isolation, latrine score and family support) showed significant geographic variability in their effect on rates of adverse outcome. Accounting for this modest non-stationary effect through geographically weighted regression increased the adjusted R2 to 0.71. Conclusions The community exploration was successful in identifying context-specific determinants of maternal health. The results highlight the need for designing targeted interventions that address the place-specific social determinants of maternal health in the study area. The geographic process of identifying and measuring these determinants, therefore, has implications for multisectoral collaboration.
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spelling ir-11408-43982022-06-27T13:49:06Z Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study Makanga, Prestige Tatenda Sacoor, Charfudin Schuurman, Nadine Lee, Tang Vilanculo, Faustino Carlos Munguambe, Khatia Boene, Helena Ukah, Ugochinyere Vivian Vidler, Marianne Magee, Laura A Sevene, Esperanca von Dadelszen, Peter Firoz, Tabassum CLIP Working Group maternal and perinatal outcomes Place-specific factors Southern Mozambique cohort study Objectives To identify and measure the place-specific determinants that are associated with adverse maternal and perinatal outcomes in the southern region of Mozambique. Design Retrospective cohort study. Choice of variables informed by literature and Delphi consensus. Setting Study conducted during the baseline phase of a community level intervention for pre-eclampsia that was led by community health workers. Participants A household census identified 50493 households that were home to 80483 women of reproductive age (age 12–49 years). Of these women, 14617 had been pregnant in the 12 months prior to the census, of which 9172 (61.6%) had completed their pregnancies. Primary and secondary outcome measures A combined fetal, maternal and neonatal outcome was calculated for all women with completed pregnancies. Results A total of six variables were statistically significant (p≤0.05) in explaining the combined outcome. These included: geographic isolation, flood proneness,access to an improved latrine, average age of reproductive age woman, family support and fertility rates. The performance of the ordinary least squares model was an adjusted R2 =0.69. Three of the variables (isolation, latrine score and family support) showed significant geographic variability in their effect on rates of adverse outcome. Accounting for this modest non-stationary effect through geographically weighted regression increased the adjusted R2 to 0.71. Conclusions The community exploration was successful in identifying context-specific determinants of maternal health. The results highlight the need for designing targeted interventions that address the place-specific social determinants of maternal health in the study area. The geographic process of identifying and measuring these determinants, therefore, has implications for multisectoral collaboration. 2021-06-07T13:42:09Z 2021-06-07T13:42:09Z 2019 Article 2044-6055 https://bmjopen.bmj.com/content/bmjopen/9/2/e024042.full.pdf http://hdl.handle.net/11408/4398 en BMJ Open;Vol.9 open BMJ Publishing Group
spellingShingle maternal and perinatal outcomes
Place-specific factors
Southern Mozambique
cohort study
Makanga, Prestige Tatenda
Sacoor, Charfudin
Schuurman, Nadine
Lee, Tang
Vilanculo, Faustino Carlos
Munguambe, Khatia
Boene, Helena
Ukah, Ugochinyere Vivian
Vidler, Marianne
Magee, Laura A
Sevene, Esperanca
von Dadelszen, Peter
Firoz, Tabassum
CLIP Working Group
Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study
title Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study
title_full Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study
title_fullStr Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study
title_full_unstemmed Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study
title_short Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study
title_sort place-specific factors associated with adverse maternal and perinatal outcomes in southern mozambique: a retrospective cohort study
topic maternal and perinatal outcomes
Place-specific factors
Southern Mozambique
cohort study
url https://bmjopen.bmj.com/content/bmjopen/9/2/e024042.full.pdf
http://hdl.handle.net/11408/4398
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