The relationship between target-class and the physicochemical properties of antibacterial drugs
The discovery of novel mechanism of action (MOA) antibacterials has been associated with the concept that antibacterial drugs occupy a differentiated region of physicochemical space compared to human-targeted drugs. With, in broad terms, antibacterials having higher molecular weight, lower log P and...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022
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| Subjects: | |
| Online Access: | https://doi.org/10.1016/j.bmc.2015.04.063 http://hdl.handle.net/11408/4924 |
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