Novel anti-Plasmodial hits identified by virtual screening of the ZINC database

Increased resistance of Plasmodium falciparum to most available drugs challenges the control of malaria. Studies with protease inhibitors have suggested important roles for the falcipain family of cysteine proteases. These enzymes act in concert with other proteases to hydrolyze host erythrocyte hem...

Full description

Saved in:
Bibliographic Details
Main Authors: Mugumbate, Grace, Newton, Ana S., Rosenthal, Philip J., Gut, Jiri, Moreira, Rui, Chibale, Kelly, Guedes, Rita C.
Format: Article
Language:English
Published: Springer 2022
Subjects:
Online Access:https://doi.org/10.1007/s10822-013-9685-z
http://hdl.handle.net/11408/4921
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items