Bovine humoral immune responses to Haemonchus placei excretory secretory antigens
immune response of calves against excretory secretory (ES) products of adult Haemonchus placei was studied. The ES products of adult H. placei comprise at least ten polypeptides with molecular weights ranging from 10 to over 100 kDa. A primary infection of calves with H. placei did not result in a m...
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Elsevier
2015
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Online Access: | http://www.sciencedirect.com.access.msu.ac.zw:2048/science/article/pii/S0304401796009508 |
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author | Schallig, Henk D. F. H. Moyo, Doreen Z. Hendrikx, Wim M. L. Eysker, Maarten |
author_facet | Schallig, Henk D. F. H. Moyo, Doreen Z. Hendrikx, Wim M. L. Eysker, Maarten |
author_sort | Schallig, Henk D. F. H. |
collection | DSpace |
description | immune response of calves against excretory secretory (ES) products of adult Haemonchus placei was studied. The ES products of adult H. placei comprise at least ten polypeptides with molecular weights ranging from 10 to over 100 kDa. A primary infection of calves with H. placei did not result in a marked elevation of IgG serum antibodies reactive to ES antigens as demonstrated by ELISA. Immunoblotting experiments revealed that sera of primary infected calves recognised a 50 kDa antigen in most cases. An increase in the level of serum IgG antibodies was observed after trickle infections. The secondary immune response coincided with the recognition of a group of three ES antigens of around 50-55 kDa and one protein with a molecular weight of 24 kDa. |
format | Article |
id | ir-11408-675 |
institution | My University |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | dspace |
spelling | ir-11408-6752022-06-27T13:49:06Z Bovine humoral immune responses to Haemonchus placei excretory secretory antigens Schallig, Henk D. F. H. Moyo, Doreen Z. Hendrikx, Wim M. L. Eysker, Maarten Haemonchus placei, cattle-nematoda, immune response-nematoda, excretory secretory products immune response of calves against excretory secretory (ES) products of adult Haemonchus placei was studied. The ES products of adult H. placei comprise at least ten polypeptides with molecular weights ranging from 10 to over 100 kDa. A primary infection of calves with H. placei did not result in a marked elevation of IgG serum antibodies reactive to ES antigens as demonstrated by ELISA. Immunoblotting experiments revealed that sera of primary infected calves recognised a 50 kDa antigen in most cases. An increase in the level of serum IgG antibodies was observed after trickle infections. The secondary immune response coincided with the recognition of a group of three ES antigens of around 50-55 kDa and one protein with a molecular weight of 24 kDa. 2015-09-18T07:39:55Z 2015-09-18T07:39:55Z 1996 Article 0304-4017 http://www.sciencedirect.com.access.msu.ac.zw:2048/science/article/pii/S0304401796009508 en Veterinary Parastology;Vol. 65; p. 289-296 none Elsevier |
spellingShingle | Haemonchus placei, cattle-nematoda, immune response-nematoda, excretory secretory products Schallig, Henk D. F. H. Moyo, Doreen Z. Hendrikx, Wim M. L. Eysker, Maarten Bovine humoral immune responses to Haemonchus placei excretory secretory antigens |
title | Bovine humoral immune responses to Haemonchus placei excretory secretory antigens |
title_full | Bovine humoral immune responses to Haemonchus placei excretory secretory antigens |
title_fullStr | Bovine humoral immune responses to Haemonchus placei excretory secretory antigens |
title_full_unstemmed | Bovine humoral immune responses to Haemonchus placei excretory secretory antigens |
title_short | Bovine humoral immune responses to Haemonchus placei excretory secretory antigens |
title_sort | bovine humoral immune responses to haemonchus placei excretory secretory antigens |
topic | Haemonchus placei, cattle-nematoda, immune response-nematoda, excretory secretory products |
url | http://www.sciencedirect.com.access.msu.ac.zw:2048/science/article/pii/S0304401796009508 |
work_keys_str_mv | AT schallighenkdfh bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens AT moyodoreenz bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens AT hendrikxwimml bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens AT eyskermaarten bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens |