Bovine humoral immune responses to Haemonchus placei excretory secretory antigens

immune response of calves against excretory secretory (ES) products of adult Haemonchus placei was studied. The ES products of adult H. placei comprise at least ten polypeptides with molecular weights ranging from 10 to over 100 kDa. A primary infection of calves with H. placei did not result in a m...

Full description

Saved in:
Bibliographic Details
Main Authors: Schallig, Henk D. F. H., Moyo, Doreen Z., Hendrikx, Wim M. L., Eysker, Maarten
Format: Article
Language:English
Published: Elsevier 2015
Subjects:
Online Access:http://www.sciencedirect.com.access.msu.ac.zw:2048/science/article/pii/S0304401796009508
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1779905251118153728
author Schallig, Henk D. F. H.
Moyo, Doreen Z.
Hendrikx, Wim M. L.
Eysker, Maarten
author_facet Schallig, Henk D. F. H.
Moyo, Doreen Z.
Hendrikx, Wim M. L.
Eysker, Maarten
author_sort Schallig, Henk D. F. H.
collection DSpace
description immune response of calves against excretory secretory (ES) products of adult Haemonchus placei was studied. The ES products of adult H. placei comprise at least ten polypeptides with molecular weights ranging from 10 to over 100 kDa. A primary infection of calves with H. placei did not result in a marked elevation of IgG serum antibodies reactive to ES antigens as demonstrated by ELISA. Immunoblotting experiments revealed that sera of primary infected calves recognised a 50 kDa antigen in most cases. An increase in the level of serum IgG antibodies was observed after trickle infections. The secondary immune response coincided with the recognition of a group of three ES antigens of around 50-55 kDa and one protein with a molecular weight of 24 kDa.
format Article
id ir-11408-675
institution My University
language English
publishDate 2015
publisher Elsevier
record_format dspace
spelling ir-11408-6752022-06-27T13:49:06Z Bovine humoral immune responses to Haemonchus placei excretory secretory antigens Schallig, Henk D. F. H. Moyo, Doreen Z. Hendrikx, Wim M. L. Eysker, Maarten Haemonchus placei, cattle-nematoda, immune response-nematoda, excretory secretory products immune response of calves against excretory secretory (ES) products of adult Haemonchus placei was studied. The ES products of adult H. placei comprise at least ten polypeptides with molecular weights ranging from 10 to over 100 kDa. A primary infection of calves with H. placei did not result in a marked elevation of IgG serum antibodies reactive to ES antigens as demonstrated by ELISA. Immunoblotting experiments revealed that sera of primary infected calves recognised a 50 kDa antigen in most cases. An increase in the level of serum IgG antibodies was observed after trickle infections. The secondary immune response coincided with the recognition of a group of three ES antigens of around 50-55 kDa and one protein with a molecular weight of 24 kDa. 2015-09-18T07:39:55Z 2015-09-18T07:39:55Z 1996 Article 0304-4017 http://www.sciencedirect.com.access.msu.ac.zw:2048/science/article/pii/S0304401796009508 en Veterinary Parastology;Vol. 65; p. 289-296 none Elsevier
spellingShingle Haemonchus placei, cattle-nematoda, immune response-nematoda, excretory secretory products
Schallig, Henk D. F. H.
Moyo, Doreen Z.
Hendrikx, Wim M. L.
Eysker, Maarten
Bovine humoral immune responses to Haemonchus placei excretory secretory antigens
title Bovine humoral immune responses to Haemonchus placei excretory secretory antigens
title_full Bovine humoral immune responses to Haemonchus placei excretory secretory antigens
title_fullStr Bovine humoral immune responses to Haemonchus placei excretory secretory antigens
title_full_unstemmed Bovine humoral immune responses to Haemonchus placei excretory secretory antigens
title_short Bovine humoral immune responses to Haemonchus placei excretory secretory antigens
title_sort bovine humoral immune responses to haemonchus placei excretory secretory antigens
topic Haemonchus placei, cattle-nematoda, immune response-nematoda, excretory secretory products
url http://www.sciencedirect.com.access.msu.ac.zw:2048/science/article/pii/S0304401796009508
work_keys_str_mv AT schallighenkdfh bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens
AT moyodoreenz bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens
AT hendrikxwimml bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens
AT eyskermaarten bovinehumoralimmuneresponsestohaemonchusplaceiexcretorysecretoryantigens