Nanodrug delivery systems in cancer therapy
Cancer burdens most world budgets particularly those in developing countries as current therapeutic options remain challenged with high costs affecting accessibility to many. At a drug designing and delivery scale, most chemotherapeutic agents are too hydrophobic, reducing bioavailability to biologi...
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| Format: | book part |
| Language: | English |
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Elsevier
2023
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| Online Access: | https://cris.library.msu.ac.zw//handle/11408/5519 https://doi.org/10.1016/B978-0-12-824408-1.00002-8 |
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| _version_ | 1779905262478426112 |
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| author | Andrew G. Mtewa Jonathan T. Bvunzawabaya Fanuel Lampiao |
| author2 | Chemistry Section, Malawi Institute of Technology, Malawi University of Science and Technology, Thyolo, Malawi. |
| author_facet | Chemistry Section, Malawi Institute of Technology, Malawi University of Science and Technology, Thyolo, Malawi. Andrew G. Mtewa Jonathan T. Bvunzawabaya Fanuel Lampiao |
| author_sort | Andrew G. Mtewa |
| collection | DSpace |
| description | Cancer burdens most world budgets particularly those in developing countries as current therapeutic options remain challenged with high costs affecting accessibility to many. At a drug designing and delivery scale, most chemotherapeutic agents are too hydrophobic, reducing bioavailability to biological targets. Other issues that challenge most current cancer drugs include drug resistance and poor selectivity leading to toxicity. Formulation of nanoparticles as drug carriers has in recent years proven to be a solution to many of the challenges that are posed by chemotherapy. Various drug carriers from the micro scale to the nanoscale have been discussed to determine how the technology can be used to reduce the burden of cancer in the future. |
| format | book part |
| id | ir-11408-5519 |
| institution | My University |
| language | English |
| publishDate | 2023 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | ir-11408-55192023-04-05T07:10:56Z Nanodrug delivery systems in cancer therapy Andrew G. Mtewa Jonathan T. Bvunzawabaya Fanuel Lampiao Chemistry Section, Malawi Institute of Technology, Malawi University of Science and Technology, Thyolo, Malawi. Department of Biomedical Sciences, Kamuzu University of Health Sciences, Blantyre, Malawi; Africa Center of Excellence in Public Health and Herbal Medicine (ACEPHEM), Kamuzu University of Health Sciences, Blantyre, Malawi; Department of Chemical Technology, Midlands State University, Gweru, Zimbabwe Department of Biomedical Sciences, Kamuzu University of Health Sciences, Blantyre, Malawi; Africa Center of Excellence in Public Health and Herbal Medicine (ACEPHEM), Kamuzu University of Health Sciences, Blantyre, Malawi, Biomolecules Biochemistry applications Drugs Toxicology Pharmacology Bioorganic chemistry Molecular biology Systems biology Therapeutic procedure Microsphere Liposomes Nanofibers Nanodiamonds Cancer burden Dendrimer Drug release Drug covalent bonding Cancer burdens most world budgets particularly those in developing countries as current therapeutic options remain challenged with high costs affecting accessibility to many. At a drug designing and delivery scale, most chemotherapeutic agents are too hydrophobic, reducing bioavailability to biological targets. Other issues that challenge most current cancer drugs include drug resistance and poor selectivity leading to toxicity. Formulation of nanoparticles as drug carriers has in recent years proven to be a solution to many of the challenges that are posed by chemotherapy. Various drug carriers from the micro scale to the nanoscale have been discussed to determine how the technology can be used to reduce the burden of cancer in the future. 239 254 2023-04-05T07:10:55Z 2023-04-05T07:10:55Z 2022 book part https://cris.library.msu.ac.zw//handle/11408/5519 https://doi.org/10.1016/B978-0-12-824408-1.00002-8 en Applications of Nanotechnology in Drug Discovery and Delivery: A volume in Drug Discovery Update 978-0-12-824408-1 https://doi.org/10.1016/C2020-0-01697-X open Elsevier |
| spellingShingle | Biomolecules Biochemistry applications Drugs Toxicology Pharmacology Bioorganic chemistry Molecular biology Systems biology Therapeutic procedure Microsphere Liposomes Nanofibers Nanodiamonds Cancer burden Dendrimer Drug release Drug covalent bonding Andrew G. Mtewa Jonathan T. Bvunzawabaya Fanuel Lampiao Nanodrug delivery systems in cancer therapy |
| title | Nanodrug delivery systems in cancer therapy |
| title_full | Nanodrug delivery systems in cancer therapy |
| title_fullStr | Nanodrug delivery systems in cancer therapy |
| title_full_unstemmed | Nanodrug delivery systems in cancer therapy |
| title_short | Nanodrug delivery systems in cancer therapy |
| title_sort | nanodrug delivery systems in cancer therapy |
| topic | Biomolecules Biochemistry applications Drugs Toxicology Pharmacology Bioorganic chemistry Molecular biology Systems biology Therapeutic procedure Microsphere Liposomes Nanofibers Nanodiamonds Cancer burden Dendrimer Drug release Drug covalent bonding |
| url | https://cris.library.msu.ac.zw//handle/11408/5519 https://doi.org/10.1016/B978-0-12-824408-1.00002-8 |
| work_keys_str_mv | AT andrewgmtewa nanodrugdeliverysystemsincancertherapy AT jonathantbvunzawabaya nanodrugdeliverysystemsincancertherapy AT fanuellampiao nanodrugdeliverysystemsincancertherapy |