TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species
TIBLE is a web-based resource that provides easy access to data on the minimal inhibitory concentrations for small molecules against several mycobacterial species, as well as the target binding and off-target predictions for Mycobacterium tuberculosis. The current version of the database holds the a...
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| Format: | Article |
| Language: | English |
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Oxford University Press
2022
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| Online Access: | https://doi.org/10.1093/database/bax041 http://www-cryst.bioc.cam.ac.uk/tible/ http://hdl.handle.net/11408/4882 |
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| _version_ | 1779905648239050752 |
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| author | Malhotra, Sony Mugumbate, Grace Blundel, Tom L Higueruelo, Alicia P |
| author_facet | Malhotra, Sony Mugumbate, Grace Blundel, Tom L Higueruelo, Alicia P |
| author_sort | Malhotra, Sony |
| collection | DSpace |
| description | TIBLE is a web-based resource that provides easy access to data on the minimal inhibitory concentrations for small molecules against several mycobacterial species, as well as the target binding and off-target predictions for Mycobacterium tuberculosis. The current version of the database holds the activity data for more than 19 000 distinct small molecules against 39 mycobacterial species, binding data for 106 Mycobacterium tuberculosis target proteins and predictions for their potential off-targets. The resource integrates disparate public data and methods to provide easy access to the minimum inhibitory concentration and binding data, facilitation of data sharing, and identification of small molecules and targets for development of anti-tuberculosis therapeutics. |
| format | Article |
| id | ir-11408-4882 |
| institution | My University |
| language | English |
| publishDate | 2022 |
| publisher | Oxford University Press |
| record_format | dspace |
| spelling | ir-11408-48822022-06-27T13:49:06Z TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species Malhotra, Sony Mugumbate, Grace Blundel, Tom L Higueruelo, Alicia P TIBLE Mycobacterium tuberculosis Anti-tuberculosis therapeutics TIBLE is a web-based resource that provides easy access to data on the minimal inhibitory concentrations for small molecules against several mycobacterial species, as well as the target binding and off-target predictions for Mycobacterium tuberculosis. The current version of the database holds the activity data for more than 19 000 distinct small molecules against 39 mycobacterial species, binding data for 106 Mycobacterium tuberculosis target proteins and predictions for their potential off-targets. The resource integrates disparate public data and methods to provide easy access to the minimum inhibitory concentration and binding data, facilitation of data sharing, and identification of small molecules and targets for development of anti-tuberculosis therapeutics. 2022-06-02T11:25:38Z 2022-06-02T11:25:38Z 2017 Article 1758-0463 https://doi.org/10.1093/database/bax041 http://www-cryst.bioc.cam.ac.uk/tible/ http://hdl.handle.net/11408/4882 en Database;Vol. 2017: p. 1-7 open Oxford University Press |
| spellingShingle | TIBLE Mycobacterium tuberculosis Anti-tuberculosis therapeutics Malhotra, Sony Mugumbate, Grace Blundel, Tom L Higueruelo, Alicia P TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species |
| title | TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species |
| title_full | TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species |
| title_fullStr | TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species |
| title_full_unstemmed | TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species |
| title_short | TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species |
| title_sort | tible: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species |
| topic | TIBLE Mycobacterium tuberculosis Anti-tuberculosis therapeutics |
| url | https://doi.org/10.1093/database/bax041 http://www-cryst.bioc.cam.ac.uk/tible/ http://hdl.handle.net/11408/4882 |
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