Gene drives in malaria control: what we need to know
Gene drives are being used to enhance a DNA sequence’s likelihood of passing between generations via sexual reproduction. Gene drives can be deployed to manipulate natural populations. They can be used to suppress populations by reducing the number of individuals in a population or to modify populat...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Open Access
2022
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| Online Access: | https://www.tandfonline.com/doi/epub/10.1080/13102818.2021.1996269?needAccess=true http://hdl.handle.net/11408/4762 |
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| author | Mudziwapasi, Reagan Changara, Munyaradzi Christopher Ndudzo, Abigarl Kaseke, Tinotenda Godobo, Farai Mtemeli, Floryn L. Shoko, Ryman Songwe, Fanuel Ndlovu, Sakhile Mlambo, Sibonani Sandra |
| author_facet | Mudziwapasi, Reagan Changara, Munyaradzi Christopher Ndudzo, Abigarl Kaseke, Tinotenda Godobo, Farai Mtemeli, Floryn L. Shoko, Ryman Songwe, Fanuel Ndlovu, Sakhile Mlambo, Sibonani Sandra |
| author_sort | Mudziwapasi, Reagan |
| collection | DSpace |
| description | Gene drives are being used to enhance a DNA sequence’s likelihood of passing between generations via sexual reproduction. Gene drives can be deployed to manipulate natural populations. They can be used to suppress populations by reducing the number of individuals in a population or to modify populations. There are more than 3000 mosquito species in the world, some of which are vectors of diseases. Malaria is a typical disease whose vectors are mosquitoes. It affects mostly tropical countries. It kills many people annually, many of whom are children. Interventions currently in use, such as indoor residual spraying and mosquito nets, are proving insufficient to eradicate malaria. Gene drives can be used in different ways to control mosquito populations or to eliminate mosquito species, thereby reducing malaria cases and deaths. This can occur through population replacement or suppression. However, before the elimination of any mosquito species for malaria control, it is necessary to consider the effects of such an action. Additionally, there is a need to review the options available for the control of mosquitoes and to create awareness of the benefits and risks of such an action. This paper, therefore, looks at the role of mosquitoes in the environment, the methods of controlling mosquitoes and malaria and necessary considerations when using gene drives inter alia. |
| format | Article |
| id | ir-11408-4762 |
| institution | My University |
| language | English |
| publishDate | 2022 |
| publisher | Taylor & Francis Open Access |
| record_format | dspace |
| spelling | ir-11408-47622022-06-27T13:49:06Z Gene drives in malaria control: what we need to know Mudziwapasi, Reagan Changara, Munyaradzi Christopher Ndudzo, Abigarl Kaseke, Tinotenda Godobo, Farai Mtemeli, Floryn L. Shoko, Ryman Songwe, Fanuel Ndlovu, Sakhile Mlambo, Sibonani Sandra plasmodium malaria mosquito control genome editing species elimination Gene drives are being used to enhance a DNA sequence’s likelihood of passing between generations via sexual reproduction. Gene drives can be deployed to manipulate natural populations. They can be used to suppress populations by reducing the number of individuals in a population or to modify populations. There are more than 3000 mosquito species in the world, some of which are vectors of diseases. Malaria is a typical disease whose vectors are mosquitoes. It affects mostly tropical countries. It kills many people annually, many of whom are children. Interventions currently in use, such as indoor residual spraying and mosquito nets, are proving insufficient to eradicate malaria. Gene drives can be used in different ways to control mosquito populations or to eliminate mosquito species, thereby reducing malaria cases and deaths. This can occur through population replacement or suppression. However, before the elimination of any mosquito species for malaria control, it is necessary to consider the effects of such an action. Additionally, there is a need to review the options available for the control of mosquitoes and to create awareness of the benefits and risks of such an action. This paper, therefore, looks at the role of mosquitoes in the environment, the methods of controlling mosquitoes and malaria and necessary considerations when using gene drives inter alia. 2022-03-24T14:13:38Z 2022-03-24T14:13:38Z 2021 Article 1314-3530 https://www.tandfonline.com/doi/epub/10.1080/13102818.2021.1996269?needAccess=true http://hdl.handle.net/11408/4762 en Biotechnology and Biotechnological Equipment;Vol.25 , Iss.1 open Taylor & Francis Open Access |
| spellingShingle | plasmodium malaria mosquito control genome editing species elimination Mudziwapasi, Reagan Changara, Munyaradzi Christopher Ndudzo, Abigarl Kaseke, Tinotenda Godobo, Farai Mtemeli, Floryn L. Shoko, Ryman Songwe, Fanuel Ndlovu, Sakhile Mlambo, Sibonani Sandra Gene drives in malaria control: what we need to know |
| title | Gene drives in malaria control: what we need to know |
| title_full | Gene drives in malaria control: what we need to know |
| title_fullStr | Gene drives in malaria control: what we need to know |
| title_full_unstemmed | Gene drives in malaria control: what we need to know |
| title_short | Gene drives in malaria control: what we need to know |
| title_sort | gene drives in malaria control: what we need to know |
| topic | plasmodium malaria mosquito control genome editing species elimination |
| url | https://www.tandfonline.com/doi/epub/10.1080/13102818.2021.1996269?needAccess=true http://hdl.handle.net/11408/4762 |
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