Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity

by Chigorimbo-Murefu, Nyaradzo T. L., Mugumbate, Grace, Chibale, Kelly
Published 2022

In silico comparison of antimycobacterial natural products with known antituberculosis drugs

by Espinoza-Moraga, Marlene, Njuguna, Nicholas M, Mugumbate, Grace, Caballero, Julio, Chibale, Kelly
Published 2022

3-Hydroxyisoflavanones from the stem bark of Dalbergia melanoxylon: Isolation, antimycobacterial evaluation and molecular docking studies

by Mutai, Peggoty, Heydenreich, Matthias, Thoithi, Grace, Mugumbate, Grace, Chibale, Kelly, Abiy Yenesew, Abiy
Published 2022

Novel anti-Plasmodial hits identified by virtual screening of the ZINC database

by Mugumbate, Grace, Newton, Ana S., Rosenthal, Philip J., Gut, Jiri, Moreira, Rui, Chibale, Kelly, Guedes, Rita C.
Published 2022

Synthesis and structure-activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2

by Sharma, Rajni Kant, Younis, Yassir, Mugumbate, Grace, Njoroge, Mathew, Gut, Jiri, Rosenthal, Philip J, Chibale, Kelly
Published 2022

Tetrazole-based deoxyamodiaquines: Synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents

by Tukulula, Matshawandile, Njoroge, Mathew, Mugumbate, Grace C., Gut, Jiri, Rosenthal, Philip J., Barteau, Samuel, Streckfuss, Judith, Heudi, Olivier, Kameni-Tcheudji, Jacques, Chibale, Kelly
Published 2022

Synthesis and in Vitro and in Vivo Pharmacological Evaluation of New 4-Aminoquinoline-Based Compounds

by Tukulula, Matshawandile, Njoroge, Mathew, Abay, Efrem T., Mugumbate, Grace C., Wiesner, Lubbe, Taylor, Dale, Gibhard, Liezl, Norman, Jennifer, Swart, Kenneth J., Gut, Jiri, Rosenthal, Philip J., Barteau, Samuel, Streckfuss, Judith, Kameni-Tcheudji, Jacques, Chibale, Kelly
Published 2022