“…Photodynamic antimicrobial chemotherapy (PACT) studies showed that linkage of Pcs to NPs improves their photoinactivation capability against Staphylococcus aureus and Escherichia coli. …”
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“…For decades drug discovery has concentrated on identifying ligands for ~10 Mtb targets, hence most of the identified essential proteins are not utilised in TB chemotherapy. Here computational techniques were used to identify ligands for the orphan Mtb proteins. …”
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“…They are considered a major threat to human health, because of the unavailability of vaccines or limited chemotherapy even in the developed parts of the world, although developing countries are carrying the major part of the burden Sub Saharan African countries, including South Africa are mostly affected by respiratory infections, diarrhea, HIV/AIDS, tuberculosis and malaria [2,3] The continued resurfacing of antibiotic- resistant infections drives research to produce better drugs to combat the more resistant pathogens [4]. …”
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“…Formulation of nanoparticles as drug carriers has in recent years proven to be a solution to many of the challenges that are posed by chemotherapy. Various drug carriers from the micro scale to the nanoscale have been discussed to determine how the technology can be used to reduce the burden of cancer in the future.…”
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