Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity
Africa disproportionately bears the brunt of the global disease burden. It has the highest prevalence of infectious diseases and some of them are unique to the continent, such as tsetse-transmitted trypanosomosis. Consequently, it is imperative for Africa to find therapies to such diseases. In spite...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book chapter |
| Language: | English |
| Published: |
John Wiley & Sons, Ltd
2022
|
| Subjects: | |
| Online Access: | https://doi.org/10.1002/9781118460566.ch4 http://hdl.handle.net/11408/4893 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1779905300229259264 |
|---|---|
| author | Chigorimbo-Murefu, Nyaradzo T. L. Mugumbate, Grace Chibale, Kelly |
| author_facet | Chigorimbo-Murefu, Nyaradzo T. L. Mugumbate, Grace Chibale, Kelly |
| author_sort | Chigorimbo-Murefu, Nyaradzo T. L. |
| collection | DSpace |
| description | Africa disproportionately bears the brunt of the global disease burden. It has the highest prevalence of infectious diseases and some of them are unique to the continent, such as tsetse-transmitted trypanosomosis. Consequently, it is imperative for Africa to find therapies to such diseases. In spite of the intellectual and scientific capacity on the continent, as well as the rich natural resources it possesses, Africa is yet to supply a drug on the market. This chapter discusses some of the platforms that will enable Africa to effectively participate in the discovery of new drug entities. The application of these technologies to natural products is explored in detail and their relevance to Africa highlighted. |
| format | Book chapter |
| id | ir-11408-4893 |
| institution | My University |
| language | English |
| publishDate | 2022 |
| publisher | John Wiley & Sons, Ltd |
| record_format | dspace |
| spelling | ir-11408-48932022-06-28T07:39:58Z Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity Chigorimbo-Murefu, Nyaradzo T. L. Mugumbate, Grace Chibale, Kelly Natural Product-Based Drug Discovery Drug discovery Africa African biodiversity Africa disproportionately bears the brunt of the global disease burden. It has the highest prevalence of infectious diseases and some of them are unique to the continent, such as tsetse-transmitted trypanosomosis. Consequently, it is imperative for Africa to find therapies to such diseases. In spite of the intellectual and scientific capacity on the continent, as well as the rich natural resources it possesses, Africa is yet to supply a drug on the market. This chapter discusses some of the platforms that will enable Africa to effectively participate in the discovery of new drug entities. The application of these technologies to natural products is explored in detail and their relevance to Africa highlighted. 2022-06-28T07:39:58Z 2022-06-28T07:39:58Z 2014 Book chapter 9781118460610 9781118460566 DOI:10.1002/9781118460566 https://doi.org/10.1002/9781118460566.ch4 http://hdl.handle.net/11408/4893 en Novel Plant Bioresources: Applications in Food, Medicine and Cosmetics;Chapter 4, pages 57-67 open John Wiley & Sons, Ltd |
| spellingShingle | Natural Product-Based Drug Discovery Drug discovery Africa African biodiversity Chigorimbo-Murefu, Nyaradzo T. L. Mugumbate, Grace Chibale, Kelly Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity |
| title | Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity |
| title_full | Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity |
| title_fullStr | Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity |
| title_full_unstemmed | Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity |
| title_short | Enabling Technologies to Facilitate Natural Product-Based Drug Discovery from African Biodiversity |
| title_sort | enabling technologies to facilitate natural product-based drug discovery from african biodiversity |
| topic | Natural Product-Based Drug Discovery Drug discovery Africa African biodiversity |
| url | https://doi.org/10.1002/9781118460566.ch4 http://hdl.handle.net/11408/4893 |
| work_keys_str_mv | AT chigorimbomurefunyaradzotl enablingtechnologiestofacilitatenaturalproductbaseddrugdiscoveryfromafricanbiodiversity AT mugumbategrace enablingtechnologiestofacilitatenaturalproductbaseddrugdiscoveryfromafricanbiodiversity AT chibalekelly enablingtechnologiestofacilitatenaturalproductbaseddrugdiscoveryfromafricanbiodiversity |