Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode
Nitrogen doped carbon nanodots (NDCNDs) and nanosized cobalt tetra aminophenoxy phthalocyanines (CoTAPhPcNPs) modified glassy carbon electrodes have been successfully used in the simultaneous detection of aspirin (ASA), ibuprofen (IBU) and indomethacin (INDO). Scanning electron microscopy (SEM), tra...
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Elsevier B.V.
2021
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| author | Dondo, Nyaradzai Shumba, Munyaradzi Moyo, Mambo Nyoni, Stephen |
| author_facet | Dondo, Nyaradzai Shumba, Munyaradzi Moyo, Mambo Nyoni, Stephen |
| author_sort | Dondo, Nyaradzai |
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| description | Nitrogen doped carbon nanodots (NDCNDs) and nanosized cobalt tetra aminophenoxy phthalocyanines (CoTAPhPcNPs) modified glassy carbon electrodes have been successfully used in the simultaneous detection of aspirin (ASA), ibuprofen (IBU) and indomethacin (INDO). Scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV–Vis spectroscopy, Fourier
transform infrared spectroscopy (FTIR), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to probe the nature of the synthesized nanomaterials. Sequential deposition of the nanomaterials on the glassy carbon electrode yielded CoTAPhPcNPs-NDCNDs-GCE with remarkable electrocatalytic performance. Electro-oxidation of the drugs at the electrode surface was first order. This work demonstrates the synergic effect of the two nanomaterials towards simultaneous electrocatalytic detection of the drugs. Superior detection limits of ASA, IBU and INDO being 9.66 10
9 M, 4.19 10 9 M and 7.2 10 9 M, respectively, were
obtained using differential pulse voltammetry. The developed sensor could detect two of the three (ibuprofen and indomethacin) simultaneously at significantly different potentials and exhibited remarkable reproducibility after a regeneration step. |
| format | Article |
| id | ir-11408-4153 |
| institution | My University |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier B.V. |
| record_format | dspace |
| spelling | ir-11408-41532022-06-27T13:49:06Z Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode Dondo, Nyaradzai Shumba, Munyaradzi Moyo, Mambo Nyoni, Stephen Nanosized cobalt tetra aminophenoxy phthalocyanine Carbon nanodots Electro-detection Nitrogen doped carbon nanodots (NDCNDs) and nanosized cobalt tetra aminophenoxy phthalocyanines (CoTAPhPcNPs) modified glassy carbon electrodes have been successfully used in the simultaneous detection of aspirin (ASA), ibuprofen (IBU) and indomethacin (INDO). Scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV–Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to probe the nature of the synthesized nanomaterials. Sequential deposition of the nanomaterials on the glassy carbon electrode yielded CoTAPhPcNPs-NDCNDs-GCE with remarkable electrocatalytic performance. Electro-oxidation of the drugs at the electrode surface was first order. This work demonstrates the synergic effect of the two nanomaterials towards simultaneous electrocatalytic detection of the drugs. Superior detection limits of ASA, IBU and INDO being 9.66 10 9 M, 4.19 10 9 M and 7.2 10 9 M, respectively, were obtained using differential pulse voltammetry. The developed sensor could detect two of the three (ibuprofen and indomethacin) simultaneously at significantly different potentials and exhibited remarkable reproducibility after a regeneration step. 2021-05-10T13:30:37Z 2021-05-10T13:30:37Z 2020 Article 18785352 https://reader.elsevier.com/reader/sd/pii/S1878535220303361?token=922EBFACA5205B619B9E717D7E73F638BE5B9D5F1E7C11B43507C80B8777B17565569008A6DDDB0C7EC69D81417F548B&originRegion=eu-west-1&originCreation=20210510085333 http://hdl.handle.net/11408/4153 en Arabian Journal of Chemistry, Vol. 13: p. 7809-7819; open Elsevier B.V. |
| spellingShingle | Nanosized cobalt tetra aminophenoxy phthalocyanine Carbon nanodots Electro-detection Dondo, Nyaradzai Shumba, Munyaradzi Moyo, Mambo Nyoni, Stephen Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode |
| title | Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode |
| title_full | Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode |
| title_fullStr | Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode |
| title_full_unstemmed | Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode |
| title_short | Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode |
| title_sort | simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode |
| topic | Nanosized cobalt tetra aminophenoxy phthalocyanine Carbon nanodots Electro-detection |
| url | https://reader.elsevier.com/reader/sd/pii/S1878535220303361?token=922EBFACA5205B619B9E717D7E73F638BE5B9D5F1E7C11B43507C80B8777B17565569008A6DDDB0C7EC69D81417F548B&originRegion=eu-west-1&originCreation=20210510085333 http://hdl.handle.net/11408/4153 |
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