Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe
This study aims to assess antimicrobial consumption in the pediatric department of a tertiary care public hospital in Zimbabwe. Clinical records of pediatric inpatients admitted to Harare Central Hospital over a 3-week period were reviewed prospectively. Antimicrobial consumption was described as d...
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| Format: | Article |
| Language: | English |
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Taylor and Francis Ltd.
2021
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| Online Access: | https://www.tandfonline.com/doi/abs/10.1080/1120009X.2020.1734719 http://hdl.handle.net/11408/4139 |
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| author | Olaru, Ioana D. Meierkord, Anne Godman, Brian Ngwenya, Crispen Fitzgerald, Felicity Dondo, Vogai Ferrand, Rashida Kranzer, Katharina |
| author_facet | Olaru, Ioana D. Meierkord, Anne Godman, Brian Ngwenya, Crispen Fitzgerald, Felicity Dondo, Vogai Ferrand, Rashida Kranzer, Katharina |
| author_sort | Olaru, Ioana D. |
| collection | DSpace |
| description | This study aims to assess antimicrobial consumption in the pediatric department of a tertiary care public hospital in Zimbabwe.
Clinical records of pediatric inpatients admitted to Harare Central Hospital over a 3-week period were reviewed prospectively. Antimicrobial consumption was described as days of therapy per 100 inpatient days (DOT/100 PD). Adherence of antimicrobial drug prescriptions to the National Guidelines was also evaluated.
A total of 121 (93.1%) children were prescribed at least one antimicrobial out of 130 children admitted. The median age was 14 months (IQR: 3 – 48 months). Overall antimicrobial consumption was 155.4 DOT / 100 PD (95% CI 146-165.2). The most frequently prescribed antimicrobials were benzylpenicillin, gentamicin and ceftriaxone. Prescriptions were adherent to national guidelines in 57.7% of children.
This study shows that there is high antimicrobial drug usage in hospitalized children in Zimbabwe and a considerable proportion of prescriptions are non-adherent with national guidelines. |
| format | Article |
| id | ir-11408-4139 |
| institution | My University |
| language | English |
| publishDate | 2021 |
| publisher | Taylor and Francis Ltd. |
| record_format | dspace |
| spelling | ir-11408-41392022-06-27T13:49:06Z Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe Olaru, Ioana D. Meierkord, Anne Godman, Brian Ngwenya, Crispen Fitzgerald, Felicity Dondo, Vogai Ferrand, Rashida Kranzer, Katharina Antimicrobial resistance Antimicrobial consumption children Antimicrobial stewardship Zimbabwe This study aims to assess antimicrobial consumption in the pediatric department of a tertiary care public hospital in Zimbabwe. Clinical records of pediatric inpatients admitted to Harare Central Hospital over a 3-week period were reviewed prospectively. Antimicrobial consumption was described as days of therapy per 100 inpatient days (DOT/100 PD). Adherence of antimicrobial drug prescriptions to the National Guidelines was also evaluated. A total of 121 (93.1%) children were prescribed at least one antimicrobial out of 130 children admitted. The median age was 14 months (IQR: 3 – 48 months). Overall antimicrobial consumption was 155.4 DOT / 100 PD (95% CI 146-165.2). The most frequently prescribed antimicrobials were benzylpenicillin, gentamicin and ceftriaxone. Prescriptions were adherent to national guidelines in 57.7% of children. This study shows that there is high antimicrobial drug usage in hospitalized children in Zimbabwe and a considerable proportion of prescriptions are non-adherent with national guidelines. 2021-05-07T12:25:50Z 2021-05-07T12:25:50Z 2020 Article 1120009X https://www.tandfonline.com/doi/abs/10.1080/1120009X.2020.1734719 http://hdl.handle.net/11408/4139 en Journal of Chemotherapy Vol. 32; No. 8 open Taylor and Francis Ltd. |
| spellingShingle | Antimicrobial resistance Antimicrobial consumption children Antimicrobial stewardship Zimbabwe Olaru, Ioana D. Meierkord, Anne Godman, Brian Ngwenya, Crispen Fitzgerald, Felicity Dondo, Vogai Ferrand, Rashida Kranzer, Katharina Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe |
| title | Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe |
| title_full | Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe |
| title_fullStr | Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe |
| title_full_unstemmed | Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe |
| title_short | Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe |
| title_sort | assessment of antimicrobial use and prescribing practices among pediatric inpatients in zimbabwe |
| topic | Antimicrobial resistance Antimicrobial consumption children Antimicrobial stewardship Zimbabwe |
| url | https://www.tandfonline.com/doi/abs/10.1080/1120009X.2020.1734719 http://hdl.handle.net/11408/4139 |
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