Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples
Background: In the present work, an electrochemical sensor for detection of paracetamol was fabricated bymodifying a glassy carbon electrode (GCE) using multiwalled carbon nanotube (MWCNT) decorated with bismuthoxide (Bi2O3) based on using the drop dry technique. Methods: The prepared composite e...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2019
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11408/3750 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1779905350366920704 |
|---|---|
| author | Chipeture, Arthur T. Apath, Daniel Moyo, Mambo Shumba, Munyaradzi |
| author_facet | Chipeture, Arthur T. Apath, Daniel Moyo, Mambo Shumba, Munyaradzi |
| author_sort | Chipeture, Arthur T. |
| collection | DSpace |
| description | Background: In the present work, an electrochemical sensor for detection of paracetamol was fabricated bymodifying a glassy carbon electrode (GCE) using multiwalled carbon nanotube (MWCNT) decorated with bismuthoxide (Bi2O3) based on using the drop dry technique.
Methods: The prepared composite electrode was characterized by scanning electron microscopy–energy dispersiveX-ray spectroscopy (SEM–EDS), Fourier transform infrared spectroscopy (FT-IR), and cyclic voltammetry (CV).Electrochemical techniques such as cyclic voltammetry, chronoamperometry, and square wave voltammetry (SWV)were used to study the behavior of paracetamol.
Results: The modification process improved the redox kinetics of paracetamol as shown by increased peak currents.The peak current varied linearly with increment of paracetamol concentration in the range of 0.02 to 28μMwithasensitivity of 1.133μAμM−1. A detection limit of 0.0052μM was obtained.
Conclusion: The proposed method was successfully applied to determination of paracetamol in biological sampleswith recoveries in the range 94.3–98.7%. |
| format | Article |
| id | ir-11408-3750 |
| institution | My University |
| language | English |
| publishDate | 2019 |
| publisher | Springer |
| record_format | dspace |
| spelling | ir-11408-37502022-06-27T13:49:06Z Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples Chipeture, Arthur T. Apath, Daniel Moyo, Mambo Shumba, Munyaradzi Bismuth (III) oxide Multiwalled carbon nanotube Voltammetry Paracetamol Background: In the present work, an electrochemical sensor for detection of paracetamol was fabricated bymodifying a glassy carbon electrode (GCE) using multiwalled carbon nanotube (MWCNT) decorated with bismuthoxide (Bi2O3) based on using the drop dry technique. Methods: The prepared composite electrode was characterized by scanning electron microscopy–energy dispersiveX-ray spectroscopy (SEM–EDS), Fourier transform infrared spectroscopy (FT-IR), and cyclic voltammetry (CV).Electrochemical techniques such as cyclic voltammetry, chronoamperometry, and square wave voltammetry (SWV)were used to study the behavior of paracetamol. Results: The modification process improved the redox kinetics of paracetamol as shown by increased peak currents.The peak current varied linearly with increment of paracetamol concentration in the range of 0.02 to 28μMwithasensitivity of 1.133μAμM−1. A detection limit of 0.0052μM was obtained. Conclusion: The proposed method was successfully applied to determination of paracetamol in biological sampleswith recoveries in the range 94.3–98.7%. 2019-12-10T09:06:21Z 2019-12-10T09:06:21Z 2019 Article Journal of Analytical Science and Technology 10:22 2093-3371 http://hdl.handle.net/11408/3750 en open Springer |
| spellingShingle | Bismuth (III) oxide Multiwalled carbon nanotube Voltammetry Paracetamol Chipeture, Arthur T. Apath, Daniel Moyo, Mambo Shumba, Munyaradzi Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples |
| title | Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples |
| title_full | Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples |
| title_fullStr | Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples |
| title_full_unstemmed | Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples |
| title_short | Multiwalled carbon nanotubes decoratedwith bismuth (III) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples |
| title_sort | multiwalled carbon nanotubes decoratedwith bismuth (iii) oxide for electrochemicaldetection of an antipyretic and analgesicdrug paracetamol in biological samples |
| topic | Bismuth (III) oxide Multiwalled carbon nanotube Voltammetry Paracetamol |
| url | http://hdl.handle.net/11408/3750 |
| work_keys_str_mv | AT chipeturearthurt multiwalledcarbonnanotubesdecoratedwithbismuthiiioxideforelectrochemicaldetectionofanantipyreticandanalgesicdrugparacetamolinbiologicalsamples AT apathdaniel multiwalledcarbonnanotubesdecoratedwithbismuthiiioxideforelectrochemicaldetectionofanantipyreticandanalgesicdrugparacetamolinbiologicalsamples AT moyomambo multiwalledcarbonnanotubesdecoratedwithbismuthiiioxideforelectrochemicaldetectionofanantipyreticandanalgesicdrugparacetamolinbiologicalsamples AT shumbamunyaradzi multiwalledcarbonnanotubesdecoratedwithbismuthiiioxideforelectrochemicaldetectionofanantipyreticandanalgesicdrugparacetamolinbiologicalsamples |