Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach

by Mugumbate, Grace, Mendes, Vitor, Blaszczyk, Michal, Sabbah, Mohamad, Papadatos, George, Lelievre, Joel, Ballell, Lluis, Barros, David, Abell, Chris, Blundell, Tom L., Overington, John P.
Published 2022

Mycobacterial Dihydrofolate Reductase Inhibitors Identified Using Chemogenomic Methods and In Vitro Validation

by Mugumbate, Grace, Abrahams, Katherine A., Cox, Jonathan A. G., Papadatos, George, Westen, Gerard van, Lelièvre, Joël, Calus, Szymon T., Loman, Nicholas J., Ballell, Lluis, Barros, David, Overington, John P., Besra, Gurdyal S.
Published 2022

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery

by Rebollo-Lopez, María Jose, Lelièvre, Joël, Alvarez-Gomez, Daniel, Castro-Piche, Julia, Martínez-Jiménez, Francisco, Papadatos, George, Kumar, Vinod, Colmenarejo, Gonzalo, Mugumbate, Grace, Hurle, Mark, Barroso, Vanessa, Young, Rob J, Martinez-Hoyos, María, González del Río, Rubén, Bates, Robert H, Lopez-Roman, Eva Maria, Mendoza-Losana, Alfonso, Brown, James R, Alvarez-Ruiz, Emilio, Marti-Renom, Marc A, Overington, John P, Cammack, Nicholas, Ballell, Lluís, Barros-Aguire, David
Published 2022