Synthesis, stereochemistry and in vitro STD NMR and in silico HIV-1 PR enzyme-binding potential of MBH-derived inhibitors

by Tukulula, Matshawandile, Olasupo, Idris A., Mugumbate, Grace C., Lobb, Kevin A., Klein, Rosalyn, Sayed, Yasien, Tshiwawa, Tendamudzimu, Kaye, Perry T.
Published 2022

Tetrazole-based deoxyamodiaquines: Synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents

by Tukulula, Matshawandile, Njoroge, Mathew, Mugumbate, Grace C., Gut, Jiri, Rosenthal, Philip J., Barteau, Samuel, Streckfuss, Judith, Heudi, Olivier, Kameni-Tcheudji, Jacques, Chibale, Kelly
Published 2022

Synthesis and in Vitro and in Vivo Pharmacological Evaluation of New 4-Aminoquinoline-Based Compounds

by Tukulula, Matshawandile, Njoroge, Mathew, Abay, Efrem T., Mugumbate, Grace C., Wiesner, Lubbe, Taylor, Dale, Gibhard, Liezl, Norman, Jennifer, Swart, Kenneth J., Gut, Jiri, Rosenthal, Philip J., Barteau, Samuel, Streckfuss, Judith, Kameni-Tcheudji, Jacques, Chibale, Kelly
Published 2022